Sedimentary sequences deposited in subglacial paleo-lakes may be present in deep lake basins deglaciated by the retreat of Northern Hemisphere ice sheets after the Last Glacial Maximum. Such sequences represent a potential archive of ice sheet dynamics and life in subglacial environments. They may also be used as testing ground for sampling and analyses of sediments contained in Antarctic subglacial lakes. We identified the Christie Arm of Great Slave Lake as the best candidate for a paleo-subglacial lake. Seismic surveys in Christie Arm show a >150-m-thick lacustrine basin fill that is overlain by a ~20-m-thick lacustrine drape and underlain by glacial till. The continuous lacustrine drape is interpreted as postglacial sediments and the basin fill as deposits formed in a subglacial paleo-lake Christie during last glaciation. The significant thickness of the interpreted subglacial lake unit implies relatively high sedimentation rates and water inflow/outflow rates in the subglacial basin.